Likely Effective for
- Constipation. Taking senna by mouth is effective for short-term treatment of constipation. Senna is an FDA-approved nonprescription drug for adults and children ages 2 years and older. However, in children ages 3-15 years, mineral oil and a medicationcalled lactulose might be more effective than taking senna. Senna also appears to be effective for treating constipation when used in combination with psyllium or docusate sodium. In elderly people, senna plus psyllium is more effective than lactulose for treating ongoing constipation. Senna plus docusate sodium is effective for treating constipation in the elderly and in people who have undergone anorectal surgery. Taking senna appears to be as effective as lactulose, psyllium, and docusate for relieving constipation in people taking opioids or loperamide.
Possibly Effective for
- Bowel preparation before colonoscopy. Taking senna by mouth is as effective as castor oil and bisocodyl for bowel preparation. Some evidence suggests that senna is also at least as effective as polyethylene glycol for bowel preparation. However, conflicting evidence exists. It is unclear if taking senna with polyethylene glycol is more effective than taking polyethylene glycol alone. Senna appears to be less effective than sodium phosphate for bowel cleansing. However, taking a combination of senna, sodium picosulfate, and polyethylene glycol appears to be more effective than sodium phosphate for bowel preparation prior to colonoscopy. Using a combination of senna, mannitol, saline solution, and simethicone, before imaging of the bowel with a special capsule that is swallowed, seems to be more effective than using the same regimen without the senna.
Possibly Ineffective for
- Diagnostic imaging. Taking senna by mouth does not appear to improve imaging of abdominal organs.
Insufficient Evidence for
- Irritable bowel syndrome (IBS).
- Losing weight.
- Surgery of anus or rectum.
- Tears in lining of anus (anal fissures).
- Other conditions.
More evidence is needed to rate the effectiveness of senna for these uses.